EGF mediates protection against Fas-induced apoptosis by depleting and oxidizing intracellular GSH stocks.

Musallam, Lina; Ethier, Chantal; Haddad, Pierre Selim; Bilodeau, Marc

Musallam, Lina; Ethier, Chantal; Haddad, Pierre Selim; Bilodeau, Marc.

Affiliation

Musallam L; Centre de recherche, Centre hospitalier de l'Université de Montréal-Hôpital Saint-Luc, and Déartement de pharmacologie, Université de Montréal, Québec, Canada.

J Cell Physiol ; 198(1): 62-72, 2004 Jan.

Article in En | MEDLINE | ID: mdl-14584045

Subject(s)

Apoptosis/physiology; Epidermal Growth Factor/metabolism; Glutathione/metabolism; fas Receptor/metabolism; Animals; Caspase 3; Caspases/metabolism; Cells, Cultured; Enzyme Inhibitors/metabolism; ErbB Receptors/metabolism; Glutathione Reductase; Hepatocytes/cytology; Hepatocytes/metabolism; Male; Mice; Mice, Inbred BALB C; NADH, NADPH Oxidoreductases/metabolism; Oxidation-Reduction; Thioredoxin-Disulfide Reductase

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Collection: 01-internacional Database: MEDLINE Main subject: Apoptosis / Fas Receptor / Epidermal Growth Factor / Glutathione Limits: Animals Language: En Journal: J Cell Physiol Year: 2004 Document type: Article Affiliation country: Canada Country of publication: United States

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