Lamellarin D: a novel potent inhibitor of topoisomerase I.

Facompré, Michaël; Tardy, Christelle; Bal-Mahieu, Christine; Colson, Pierre; Perez, Carlos; Manzanares, Ignacio; Cuevas, Carmen; Bailly, Christian

Facompré, Michaël; Tardy, Christelle; Bal-Mahieu, Christine; Colson, Pierre; Perez, Carlos; Manzanares, Ignacio; Cuevas, Carmen; Bailly, Christian.

Affiliation

Facompré M; Institut National de la Santé et de la Recherche Médicale U-524 and Laboratoire de Pharmacologie Antitumorale du Centre Oscar Lambret, Place de Verdun, 59045 Lille, France.

Cancer Res ; 63(21): 7392-9, 2003 Nov 01.

Article in En | MEDLINE | ID: mdl-14612538

Subject(s)

Antineoplastic Agents/pharmacology; Coumarins/pharmacology; Enzyme Inhibitors/pharmacology; Heterocyclic Compounds, 4 or More Rings/pharmacology; Isoquinolines/pharmacology; Topoisomerase I Inhibitors; Animals; Antineoplastic Agents/chemistry; Cattle; Coumarins/chemistry; DNA/drug effects; DNA/metabolism; DNA Topoisomerases, Type I/chemistry; DNA Topoisomerases, Type I/metabolism; Enzyme Inhibitors/chemistry; Heterocyclic Compounds, 4 or More Rings/chemistry; Isoquinolines/chemistry; Leukemia P388/drug therapy; Leukemia P388/enzymology; Mice; Models, Molecular

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Collection: 01-internacional Database: MEDLINE Main subject: Coumarins / Enzyme Inhibitors / Topoisomerase I Inhibitors / Heterocyclic Compounds, 4 or More Rings / Isoquinolines / Antineoplastic Agents Limits: Animals Language: En Journal: Cancer Res Year: 2003 Document type: Article Affiliation country: France Country of publication: United States

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