Transplantation of bone marrow-derived mononuclear cells in ischemic apolipoprotein E-knockout mice accelerates atherosclerosis without altering plaque composition.

Silvestre, Jean-Sébastien; Gojova, Andrea; Brun, Valérie; Potteaux, Stéphane; Esposito, Bruno; Duriez, Micheline; Clergue, Michel; Le Ricousse-Roussanne, Sophie; Barateau, Véronique; Merval, Régine; Groux, Hervé; Tobelem, Gérard; Levy, Bernard; Tedgui, Alain; Mallat, Ziad

Silvestre, Jean-Sébastien; Gojova, Andrea; Brun, Valérie; Potteaux, Stéphane; Esposito, Bruno; Duriez, Micheline; Clergue, Michel; Le Ricousse-Roussanne, Sophie; Barateau, Véronique; Merval, Régine; Groux, Hervé; Tobelem, Gérard; Levy, Bernard; Tedgui, Alain; Mallat, Ziad.

Affiliation

Silvestre JS; Institut National de la Santé et de la Recherche Médicale U541, Hôpital Lariboisière, 41, Bd de la Chapelle, 75010 Paris, France.

Circulation ; 108(23): 2839-42, 2003 Dec 09.

Article in En | MEDLINE | ID: mdl-14656923

Subject(s)

Apolipoproteins E/deficiency; Arteriosclerosis/therapy; Bone Marrow Transplantation/adverse effects; Hindlimb/blood supply; Ischemia/therapy; Neovascularization, Physiologic; Sinus of Valsalva/pathology; Animals; Apolipoproteins E/genetics; Arteriosclerosis/metabolism; Chemokine CCL2/blood; Cholesterol/blood; Disease Progression; Femoral Artery; Ligation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Safety; Treatment Failure; Vascular Endothelial Growth Factor A/blood

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Collection: 01-internacional Database: MEDLINE Main subject: Apolipoproteins E / Arteriosclerosis / Sinus of Valsalva / Bone Marrow Transplantation / Neovascularization, Physiologic / Hindlimb / Ischemia Limits: Animals Language: En Journal: Circulation Year: 2003 Document type: Article Affiliation country: France Country of publication: United States

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