Prostate tumor microenvironment alters immune cells and prevents long-term survival in an orthotopic mouse model following flt3-ligand/CD40-ligand immunotherapy.

Ciavarra, Richard P; Holterman, Daniel A; Brown, Roy R; Mangiotti, Patricia; Yousefieh, Nazita; Wright, George L; Schellhammer, Paul F; Glass, W F; Somers, Kenneth D

Ciavarra, Richard P; Holterman, Daniel A; Brown, Roy R; Mangiotti, Patricia; Yousefieh, Nazita; Wright, George L; Schellhammer, Paul F; Glass, W F; Somers, Kenneth D.

Affiliation

Ciavarra RP; Departments of Microbiology and Molecular Cell Biology, Virginia Prostate Center, Eastern Virginia Medical School, Norfolk, Virginia 23501, USA. ciavarrp@ems.edu

J Immunother ; 27(1): 13-26, 2004.

Article in En | MEDLINE | ID: mdl-14676630

Subject(s)

CD40 Ligand/therapeutic use; Membrane Proteins/therapeutic use; Prostatic Neoplasms/drug therapy; Animals; Cell Line, Tumor; Dendritic Cells/immunology; Disease Models, Animal; Disease-Free Survival; Immunosuppression Therapy; Immunotherapy; Lymphatic Metastasis; Lymphocytes, Tumor-Infiltrating/immunology; Male; Mice; Mice, Transgenic; Prostatic Neoplasms/immunology; T-Lymphocytes/immunology; T-Lymphocytes/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms / CD40 Ligand / Membrane Proteins Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Immunother Journal subject: ALERGIA E IMUNOLOGIA / NEOPLASIAS / TERAPEUTICA Year: 2004 Document type: Article Affiliation country: United States Country of publication: United States

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