Re-establishment of a normal apoptotic process as a therapeutic approach in B-CLL.

Kolb, Jean-Pierre; Kern, Catherine; Quiney, Claire; Roman, Viviana; Billard, Christian

Kolb, Jean-Pierre; Kern, Catherine; Quiney, Claire; Roman, Viviana; Billard, Christian.

Affiliation

Kolb JP; U365 INSERM, Institut Curie, 26 rue d-Ulm, 75248 Paris cedex 05, France. jpkolb@curie.fr

Curr Drug Targets Cardiovasc Haematol Disord ; 3(4): 261-86, 2003 Dec.

Article in En | MEDLINE | ID: mdl-14683470

Subject(s)

Antineoplastic Agents/pharmacology; Apoptosis/drug effects; Leukemia, Lymphocytic, Chronic, B-Cell/drug therapy; Leukemia, Lymphocytic, Chronic, B-Cell/pathology; Animals; Antineoplastic Agents/therapeutic use; Antioxidants/metabolism; Apoptosis/physiology; Caspases/metabolism; Cytokines/genetics; Cytokines/metabolism; Humans; Interferons/genetics; Interferons/metabolism; Ion Channels/agonists; Leukemia, Lymphocytic, Chronic, B-Cell/metabolism; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Nitric Oxide/metabolism; Proto-Oncogene Proteins c-bcl-2/metabolism; Tumor Necrosis Factor-alpha/genetics; Tumor Necrosis Factor-alpha/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Lymphocytic, Chronic, B-Cell / Apoptosis / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Curr Drug Targets Cardiovasc Haematol Disord Journal subject: ANGIOLOGIA / CARDIOLOGIA / HEMATOLOGIA / TERAPIA POR MEDICAMENTOS Year: 2003 Document type: Article Affiliation country: France Country of publication: Netherlands

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