Oxygen-induced DNA damage in freshly isolated brain cells compared with cultured astrocytes in the Comet assay.

Cemeli, Eduardo; Smith, Ian F; Peers, Chris; Urenjak, Jutta; Godukhin, Oleg V; Obrenovitch, Tihomir P; Anderson, Diana

Cemeli, Eduardo; Smith, Ian F; Peers, Chris; Urenjak, Jutta; Godukhin, Oleg V; Obrenovitch, Tihomir P; Anderson, Diana.

Affiliation

Cemeli E; Department of Biomedical Sciences, University of Bradford, Bradford, United Kingdom.

Teratog Carcinog Mutagen ; Suppl 2: 43-52, 2003.

Article in En | MEDLINE | ID: mdl-14691979

Subject(s)

Astrocytes/drug effects; Brain/drug effects; DNA Damage; DNA/drug effects; Free Radical Scavengers/metabolism; Oxidative Stress; Oxygen/toxicity; Animals; Ascorbic Acid/metabolism; Brain/metabolism; Catalase/metabolism; Cells, Cultured; Comet Assay; Hydrogen Peroxide/pharmacology; Male; Mice; Mice, Inbred C57BL; Rats; Rats, Wistar; Superoxide Dismutase/metabolism; Superoxides/pharmacology; Xanthine Oxidase/metabolism; Xanthines/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Oxygen / DNA Damage / Brain / DNA / Astrocytes / Free Radical Scavengers / Oxidative Stress Type of study: Prognostic_studies Limits: Animals Language: En Journal: Teratog Carcinog Mutagen Year: 2003 Document type: Article Affiliation country: United kingdom Country of publication: United States

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