Round window pH manipulation alters the ototoxicity of systemic cisplatin.

Tanaka, Fujinobu; Whitworth, Craig A; Rybak, Leonard P

Tanaka, Fujinobu; Whitworth, Craig A; Rybak, Leonard P.

Affiliation

Tanaka F; Department of Surgery, Southern Illinois University School of Medicine, P.O. Box 19638,Springfield, IL 62794-9638, USA.

Hear Res ; 187(1-2): 44-50, 2004 Jan.

Article in En | MEDLINE | ID: mdl-14698086

Subject(s)

Antineoplastic Agents/poisoning; Cisplatin/poisoning; Ear/pathology; Ear/physiology; Protons; Round Window, Ear/metabolism; Animals; Antineoplastic Agents/administration & dosage; Auditory Threshold/drug effects; Body Weight/drug effects; Cell Count; Cell Survival/drug effects; Cisplatin/administration & dosage; Evoked Potentials, Auditory, Brain Stem/drug effects; Hair Cells, Auditory/drug effects; Hair Cells, Auditory/pathology; Hydrogen-Ion Concentration; Injections, Intraperitoneal; Male; Rats; Rats, Wistar

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Collection: 01-internacional Database: MEDLINE Main subject: Protons / Round Window, Ear / Cisplatin / Ear / Antineoplastic Agents Limits: Animals Language: En Journal: Hear Res Year: 2004 Document type: Article Affiliation country: United States Country of publication: Netherlands

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