Synaptically stimulated induction of group I metabotropic glutamate receptor-dependent long-term depression and depotentiation is inhibited by prior activation of metabotropic glutamate receptors and protein kinase C.

Wu, J; Rowan, M J; Anwyl, R

Wu, J; Rowan, M J; Anwyl, R.

Affiliation

Wu J; Department of Physiology, Trinity College, Dublin 2, Ireland.

Neuroscience ; 123(2): 507-14, 2004.

Article in En | MEDLINE | ID: mdl-14698757

Subject(s)

Brain/physiology; Long-Term Potentiation/physiology; Long-Term Synaptic Depression/physiology; Protein Kinase C/metabolism; Receptors, Metabotropic Glutamate/physiology; Synapses/physiology; Animals; Brain/drug effects; Electric Stimulation; Enzyme Activation/drug effects; Enzyme Activation/physiology; Enzyme Inhibitors/pharmacology; Excitatory Amino Acid Antagonists/pharmacology; Excitatory Postsynaptic Potentials/drug effects; Excitatory Postsynaptic Potentials/physiology; Organ Culture Techniques; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate/drug effects; Synapses/drug effects

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Collection: 01-internacional Database: MEDLINE Main subject: Synapses / Brain / Protein Kinase C / Receptors, Metabotropic Glutamate / Long-Term Potentiation / Long-Term Synaptic Depression Limits: Animals Language: En Journal: Neuroscience Year: 2004 Document type: Article Affiliation country: Ireland

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