Effect of chronic viral infection on epitope selection, cytokine production, and surface phenotype of CD8 T cells and the role of IFN-gamma receptor in immune regulation.

Tewari, Kavita; Sacha, Jonah; Gao, Xiaoyan; Suresh, M

Tewari, Kavita; Sacha, Jonah; Gao, Xiaoyan; Suresh, M.

Affiliation

Tewari K; Department of Pathobiological Sciences, University of Wisconsin, Madison, WI 53706.

J Immunol ; 172(3): 1491-500, 2004 Feb 01.

Article in En | MEDLINE | ID: mdl-14734726

Subject(s)

CD8-Positive T-Lymphocytes/immunology; Cytokines/biosynthesis; Epitopes, T-Lymphocyte/biosynthesis; Immunophenotyping; Interferon-gamma/physiology; Lymphocytic Choriomeningitis/immunology; Lymphocytic choriomeningitis virus/immunology; Receptors, Interferon/physiology; Acute Disease; Animals; B-Cell Lymphoma 3 Protein; CD8-Positive T-Lymphocytes/metabolism; CD8-Positive T-Lymphocytes/virology; Cell Membrane/immunology; Cell Membrane/metabolism; Chronic Disease; DNA-Binding Proteins/biosynthesis; Epitopes, T-Lymphocyte/metabolism; Immunodominant Epitopes/biosynthesis; Immunodominant Epitopes/metabolism; Immunologic Memory; Interferon-gamma/metabolism; Mice; Mice, Inbred C57BL; Mice, Knockout; Proto-Oncogene Proteins/biosynthesis; Proto-Oncogene Proteins c-bcl-2/biosynthesis; Proto-Oncogene Proteins c-bcl-6; Receptors, Interferon/metabolism; Transcription Factors/biosynthesis; Interferon gamma Receptor

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Collection: 01-internacional Database: MEDLINE Main subject: Cytokines / Immunophenotyping / Interferon-gamma / Receptors, Interferon / CD8-Positive T-Lymphocytes / Epitopes, T-Lymphocyte / Lymphocytic Choriomeningitis / Lymphocytic choriomeningitis virus Limits: Animals Language: En Journal: J Immunol Year: 2004 Document type: Article Country of publication: United States

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