Fatal pulmonary thromboembolism after a second course of high-dose chemotherapy with autologous peripheral blood stem cell transplantation.
Pediatr Transplant
; 7(5): 400-3, 2003 Oct.
Article
in En
| MEDLINE
| ID: mdl-14738303
ABSTRACT
We describe a 4-yr-old boy with an occult primitive neuroectodermal tumor, who suffered fatal PTE after a second course of HDC with autologous PBSCT. On day + 52 after a second PBSCT, he was admitted because of respiratory distress. Respiratory failure rapidly progressed and he died within 4 days. The diagnosis of PTE was confirmed by a lung perfusion study with technetium-99m macroaggregated albumin, but too late to allow treatment. Although rare, PTE must be recognized as an important differential diagnosis when respiratory symptoms are observed after HDC with PBSCT.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pulmonary Embolism
/
Brain Neoplasms
/
Antineoplastic Combined Chemotherapy Protocols
/
Neuroectodermal Tumors, Primitive
/
Peripheral Blood Stem Cell Transplantation
Limits:
Child, preschool
/
Humans
/
Male
Language:
En
Journal:
Pediatr Transplant
Journal subject:
PEDIATRIA
/
TRANSPLANTE
Year:
2003
Document type:
Article
Affiliation country:
Japan