Pharmacokinetic disposition of multiple-dose transdermal nicotine in healthy adult smokers.

Kochak, G M; Sun, J X; Choi, R L; Piraino, A J

Kochak, G M; Sun, J X; Choi, R L; Piraino, A J.

Affiliation

Kochak GM; Drug Development Department, CIBA-GEIGY Corporation, Ardsley, New York 10502.

Pharm Res ; 9(11): 1451-5, 1992 Nov.

Article in En | MEDLINE | ID: mdl-1475232

Subject(s)

Cotinine/pharmacokinetics; Nicotine/pharmacokinetics; Administration, Cutaneous; Adult; Analysis of Variance; Blood Pressure/drug effects; Electrocardiography/drug effects; Half-Life; Heart Rate/drug effects; Humans; Male; Nicotine/administration & dosage; Nicotine/blood; Nicotine/pharmacology; Skin Absorption; Smoking

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Collection: 01-internacional Database: MEDLINE Main subject: Cotinine / Nicotine Limits: Adult / Humans / Male Language: En Journal: Pharm Res Year: 1992 Document type: Article Country of publication: United States

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