Antimalarial activity of phenazines from lapachol, beta-lapachone and its derivatives against Plasmodium falciparum in vitro and Plasmodium berghei in vivo.

de Andrade-Neto, Valter F; Goulart, Marília O F; da Silva Filho, Jorge F; da Silva, Matuzalém J; Pinto, Maria do Carmo F R; Pinto, Antônio V; Zalis, Mariano G; Carvalho, Luzia H; Krettli, Antoniana U

de Andrade-Neto, Valter F; Goulart, Marília O F; da Silva Filho, Jorge F; da Silva, Matuzalém J; Pinto, Maria do Carmo F R; Pinto, Antônio V; Zalis, Mariano G; Carvalho, Luzia H; Krettli, Antoniana U.

Affiliation

de Andrade-Neto VF; Centro de Pesquisas René Rachou, Fiocruz and Departamento de Parasitologia-Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brazil.

Bioorg Med Chem Lett ; 14(5): 1145-9, 2004 Mar 08.

Article in En | MEDLINE | ID: mdl-14980653

Subject(s)

Antimalarials/pharmacology; Naphthoquinones/pharmacology; Phenazines/pharmacology; Plasmodium berghei/drug effects; Plasmodium falciparum/drug effects; Animals; Antimalarials/chemistry; Antimalarials/therapeutic use; Dose-Response Relationship, Drug; Malaria/drug therapy; Mice; Naphthoquinones/chemistry; Naphthoquinones/therapeutic use; Phenazines/chemistry; Phenazines/therapeutic use; Plasmodium berghei/physiology; Plasmodium falciparum/physiology

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Phenazines / Plasmodium berghei / Plasmodium falciparum / Naphthoquinones / Antimalarials Limits: Animals Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2004 Document type: Article Affiliation country: Brazil

Search on Google

Add to My VHL

XML

PubMed Links