Both relative insulin resistance and defective islet beta-cell processing of proinsulin are responsible for transient hyperglycemia in extremely preterm infants.

Mitanchez-Mokhtari, Delphine; Lahlou, Najiba; Kieffer, François; Magny, Jean-François; Roger, Marc; Voyer, Marcel

Mitanchez-Mokhtari, Delphine; Lahlou, Najiba; Kieffer, François; Magny, Jean-François; Roger, Marc; Voyer, Marcel.

Affiliation

Mitanchez-Mokhtari D; Service de Réanimation Pédiatrique et Néonatale, Hôpital Necker-Enfants Malades, Paris, France. delphine.mitanchez@nck.ap-hop-paris.fr

Pediatrics ; 113(3 Pt 1): 537-41, 2004 Mar.

Article in En | MEDLINE | ID: mdl-14993546

Subject(s)

Hyperglycemia/blood; Infant, Premature, Diseases/blood; Insulin Resistance/physiology; Proinsulin/physiology; Blood Glucose; C-Peptide/blood; Female; Humans; Hyperglycemia/etiology; Infant, Newborn; Infant, Premature/physiology; Infant, Premature, Diseases/etiology; Insulin/administration & dosage; Insulin/physiology; Islets of Langerhans/physiology; Male; Proinsulin/blood; Prospective Studies

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Collection: 01-internacional Database: MEDLINE Main subject: Proinsulin / Insulin Resistance / Hyperglycemia / Infant, Premature, Diseases Type of study: Etiology_studies / Observational_studies Limits: Female / Humans / Male / Newborn Language: En Journal: Pediatrics Year: 2004 Document type: Article Affiliation country: France

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