Effect of elevating the skin temperature during topical ALA application on in vitro ALA penetration through mouse skin and in vivo PpIX production in human skin.

van den Akker, Johanna T H M; Boot, Kristian; Vernon, David I; Brown, Stanley B; Groenendijk, Laurens; van Rhoon, Gerard C; Sterenborg, Henricus J C M

van den Akker, Johanna T H M; Boot, Kristian; Vernon, David I; Brown, Stanley B; Groenendijk, Laurens; van Rhoon, Gerard C; Sterenborg, Henricus J C M.

Affiliation

van den Akker JT; Photodynamic Therapy and Optical Spectroscopy Programme, Department of Radiation Oncology, Erasmus Medical Centre-Daniel den Hoed Cancer Centre, PO Box 5201, 3008 AE Rotterdam, The Netherlands.

Photochem Photobiol Sci ; 3(3): 263-7, 2004 Mar.

Article in En | MEDLINE | ID: mdl-14993942

Subject(s)

Aminolevulinic Acid/administration & dosage; Aminolevulinic Acid/pharmacokinetics; Protoporphyrins/biosynthesis; Skin/drug effects; Skin/metabolism; Administration, Topical; Animals; Female; Hot Temperature; Humans; In Vitro Techniques; Kinetics; Male; Mice; Mice, Hairless; Photochemotherapy; Skin Temperature

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Collection: 01-internacional Database: MEDLINE Main subject: Protoporphyrins / Skin / Aminolevulinic Acid Limits: Animals / Female / Humans / Male Language: En Journal: Photochem Photobiol Sci Journal subject: BIOLOGIA / QUIMICA Year: 2004 Document type: Article Affiliation country: Netherlands

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