Development of bombesin analogs with conformationally restricted amino acid substitutions with enhanced selectivity for the orphan receptor human bombesin receptor subtype 3.

Mantey, Samuel A; Coy, David H; Entsuah, Laurence K; Jensen, Robert T

Mantey, Samuel A; Coy, David H; Entsuah, Laurence K; Jensen, Robert T.

Affiliation

Mantey SA; Digestive Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bldg. 10, Room 9C-103, 10 Center Dr., MSC 1804, Bethesda, MD 20892-1804l, USA.

J Pharmacol Exp Ther ; 310(3): 1161-70, 2004 Sep.

Article in En | MEDLINE | ID: mdl-15102928

Subject(s)

Bombesin/metabolism; Receptors, Bombesin/metabolism; 3T3 Cells; Amino Acid Substitution; Animals; Bombesin/chemistry; Bombesin/genetics; CHO Cells; Cricetinae; Humans; Mice; Mice, Inbred BALB C; Protein Conformation; Rats; Substrate Specificity

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Collection: 01-internacional Database: MEDLINE Main subject: Bombesin / Receptors, Bombesin Limits: Animals / Humans Language: En Journal: J Pharmacol Exp Ther Year: 2004 Document type: Article Affiliation country: United States Country of publication: United States

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