Importance of antioxidant and antiapoptotic effects of beta-receptor blockers in heart failure therapy.

Kawai, Keisuke; Qin, Fuzhong; Shite, Junya; Mao, Weike; Fukuoka, Shuji; Liang, Chang-Seng

Kawai, Keisuke; Qin, Fuzhong; Shite, Junya; Mao, Weike; Fukuoka, Shuji; Liang, Chang-Seng.

Affiliation

Kawai K; Cardiology Unit, Department of Medicine, University of Rochester Medical Center, Rochester, New York 14642, USA.

Am J Physiol Heart Circ Physiol ; 287(3): H1003-12, 2004 Sep.

Article in En | MEDLINE | ID: mdl-15105169

Subject(s)

Adrenergic beta-Antagonists/therapeutic use; Antioxidants/therapeutic use; Apoptosis/drug effects; Deoxyguanosine/analogs & derivatives; Heart Failure/drug therapy; 8-Hydroxy-2'-Deoxyguanosine; Animals; Cell Size; DNA, Mitochondrial/metabolism; Deoxyguanosine/metabolism; Echocardiography; Glutathione/metabolism; Glutathione Disulfide/metabolism; Heart Failure/diagnostic imaging; Heart Failure/etiology; Heart Failure/physiopathology; Hemodynamics; Myocardium/metabolism; Myocytes, Cardiac/pathology; Proto-Oncogene Proteins/metabolism; Proto-Oncogene Proteins c-bcl-2/metabolism; Rabbits; Rest; bcl-2-Associated X Protein

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Collection: 01-internacional Database: MEDLINE Main subject: Apoptosis / Adrenergic beta-Antagonists / Deoxyguanosine / Heart Failure / Antioxidants Type of study: Etiology_studies Limits: Animals Language: En Journal: Am J Physiol Heart Circ Physiol Journal subject: CARDIOLOGIA / FISIOLOGIA Year: 2004 Document type: Article Affiliation country: United States

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