Mineralocorticoid receptor antagonists do not block rapid ERK activation by aldosterone.

Rossol-Haseroth, Karin; Zhou, Qian; Braun, Sabine; Boldyreff, Brigitte; Falkenstein, Elisabeth; Wehling, Martin; Lösel, Ralf M

Rossol-Haseroth, Karin; Zhou, Qian; Braun, Sabine; Boldyreff, Brigitte; Falkenstein, Elisabeth; Wehling, Martin; Lösel, Ralf M.

Affiliation

Rossol-Haseroth K; Department of Clinical Pharmacology, Faculty of Clinical Medicine Mannheim, University of Heidelberg, 68167 Mannheim, Germany.

Biochem Biophys Res Commun ; 318(1): 281-8, 2004 May 21.

Article in En | MEDLINE | ID: mdl-15110785

Subject(s)

Aldosterone/pharmacology; Mineralocorticoid Receptor Antagonists; Mitogen-Activated Protein Kinase 1/metabolism; Mitogen-Activated Protein Kinases/metabolism; Aldosterone/metabolism; Animals; Butadienes/pharmacology; Cell Line; Cycloheximide/pharmacology; Dactinomycin/pharmacology; Dose-Response Relationship, Drug; Enzyme Activation/drug effects; Enzyme Inhibitors/pharmacology; Flavonoids/pharmacology; Hydrocortisone/pharmacology; Kidney Cortex/cytology; Kidney Cortex/metabolism; Kidney Tubules, Collecting/cytology; Mice; Mineralocorticoid Receptor Antagonists/pharmacology; Mitogen-Activated Protein Kinase 1/antagonists & inhibitors; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases/antagonists & inhibitors; Nitriles/pharmacology; Phosphorylation; Proto-Oncogene Proteins c-raf/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Mitogen-Activated Protein Kinase 1 / Mitogen-Activated Protein Kinases / Aldosterone / Mineralocorticoid Receptor Antagonists Limits: Animals Language: En Journal: Biochem Biophys Res Commun Year: 2004 Document type: Article Affiliation country: Germany Country of publication: United States

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