Down-regulation of soluble guanylyl cyclase expression by cyclic AMP is mediated by mRNA-stabilizing protein HuR.

Klöss, Stephan; Srivastava, Rashi; Mülsch, Alexander

Klöss, Stephan; Srivastava, Rashi; Mülsch, Alexander.

Affiliation

Klöss S; Institut für Kardiovaskuläre Physiologie, Johann Wolfgang v. Goethe-Universität, Frankfurt/Main, Germany. s.kloess@em.uni-frankfurt.de

Mol Pharmacol ; 65(6): 1440-51, 2004 Jun.

Article in En | MEDLINE | ID: mdl-15155837

Subject(s)

Antigens, Surface/metabolism; Cyclic AMP/pharmacology; Gene Expression/drug effects; Guanylate Cyclase/metabolism; RNA Stability/physiology; RNA-Binding Proteins/metabolism; 3' Untranslated Regions/drug effects; 3' Untranslated Regions/metabolism; Adenylyl Cyclases; Animals; Aorta; Cells, Cultured; Colforsin/pharmacology; Cyclic AMP/analogs & derivatives; Dactinomycin/pharmacology; Down-Regulation/drug effects; Drug Interactions; ELAV Proteins; ELAV-Like Protein 1; Gene Expression Regulation; Genes, fos; Guanylate Cyclase/genetics; Male; RNA Stability/drug effects; Rats; Rats, Wistar; Transcription Factor AP-1/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression / RNA-Binding Proteins / Cyclic AMP / RNA Stability / Guanylate Cyclase / Antigens, Surface Limits: Animals Language: En Journal: Mol Pharmacol Year: 2004 Document type: Article Affiliation country: Germany Country of publication: United States

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