Specific interaction of tissue-type plasminogen activator (t-PA) with annexin II on the membrane of pancreatic cancer cells activates plasminogen and promotes invasion in vitro.

Díaz, V M; Hurtado, M; Thomson, T M; Reventós, J; Paciucci, R

Díaz, V M; Hurtado, M; Thomson, T M; Reventós, J; Paciucci, R.

Affiliation

Díaz VM; Unitat de Recerca Biomèdica, Hospital Materno-Infantil, Hospitals Vall d'Hebrón, Pg Vall d'Hebrón 119-129, 08035 Barcelona, Spain.

Gut ; 53(7): 993-1000, 2004 Jul.

Article in En | MEDLINE | ID: mdl-15194650

Subject(s)

Annexin A2/metabolism; Pancreatic Neoplasms/metabolism; Plasminogen/metabolism; Tissue Plasminogen Activator/metabolism; Binding, Competitive; Cell Membrane/metabolism; Humans; Neoplasm Invasiveness; Neoplasm Proteins/metabolism; Neoplasm Proteins/physiology; Pancreatic Neoplasms/pathology; Tissue Plasminogen Activator/physiology; Tumor Cells, Cultured

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatic Neoplasms / Plasminogen / Tissue Plasminogen Activator / Annexin A2 Limits: Humans Language: En Journal: Gut Year: 2004 Document type: Article Affiliation country: Spain Country of publication: United kingdom

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