Synthesis, theoretical and structural analyses, and enantiopharmacology of 3-carboxy homologs of AMPA.

Brehm, Lotte; Greenwood, Jeremy R; Sløk, Frank A; Holm, Mai Marie; Nielsen, Birgitte; Geneser, Ulla; Stensbøl, Tine B; Bräuner-Osborne, Hans; Begtrup, Mikael; Egebjerg, Jan; Krogsgaard-Larsen, Povl

Brehm, Lotte; Greenwood, Jeremy R; Sløk, Frank A; Holm, Mai Marie; Nielsen, Birgitte; Geneser, Ulla; Stensbøl, Tine B; Bräuner-Osborne, Hans; Begtrup, Mikael; Egebjerg, Jan; Krogsgaard-Larsen, Povl.

Affiliation

Brehm L; NeuroScience PharmaBiotec Research Centre, Department of Medicinal Chemistry, The Danish University of Pharmaceutical Sciences, Copenhagen, Denmark.

Chirality ; 16(7): 452-66, 2004 Aug.

Article in En | MEDLINE | ID: mdl-15236343

Subject(s)

alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid/chemical synthesis; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid/pharmacology; Animals; CHO Cells; Chromatography, High Pressure Liquid; Circular Dichroism; Cricetinae; Crystallography, X-Ray; Electrophysiology; Glutamic Acid/metabolism; Hydrogen Bonding; Inhibitory Concentration 50; Molecular Conformation; Ovum; Rats; Receptors, Glutamate/genetics; Receptors, Glutamate/metabolism; Second Messenger Systems/drug effects; Stereoisomerism; Xenopus; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid/analogs & derivatives; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid/chemistry

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Limits: Animals Language: En Journal: Chirality Journal subject: BIOLOGIA MOLECULAR / QUIMICA Year: 2004 Document type: Article Affiliation country: Denmark Country of publication: United States

Search on Google

Add to My VHL

XML

PubMed Links