Stimulatory effect of topical application of caffeine on UVB-induced apoptosis in the epidermis of p53 and Bax knockout mice.

Lu, Yao-Ping; Lou, You-Rong; Peng, Qing-Yun; Xie, Jian-Guo; Conney, Allan H

Lu, Yao-Ping; Lou, You-Rong; Peng, Qing-Yun; Xie, Jian-Guo; Conney, Allan H.

Affiliation

Lu YP; Susan Lehman Cullman Laboratory for Cancer Research, Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers-The State University of New Jersey, 164 Frelinghuysen Road, Piscataway, NJ 08854-8020, USA.

Cancer Res ; 64(14): 5020-7, 2004 Jul 15.

Article in En | MEDLINE | ID: mdl-15256477

Subject(s)

Apoptosis/drug effects; Caffeine/pharmacology; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins/physiology; Skin/drug effects; Tumor Suppressor Protein p53/physiology; Administration, Topical; Animals; Apoptosis/radiation effects; Cell Division/drug effects; Cell Division/radiation effects; Female; Male; Mice; Mice, Hairless; Mice, Inbred C57BL; Mice, Knockout; Proto-Oncogene Proteins/genetics; Skin/cytology; Skin/radiation effects; Sunburn/etiology; Sunburn/pathology; Tumor Suppressor Protein p53/genetics; Ultraviolet Rays; bcl-2-Associated X Protein

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Collection: 01-internacional Database: MEDLINE Main subject: Skin / Caffeine / Tumor Suppressor Protein p53 / Proto-Oncogene Proteins / Apoptosis / Proto-Oncogene Proteins c-bcl-2 Type of study: Etiology_studies Limits: Animals Language: En Journal: Cancer Res Year: 2004 Document type: Article Affiliation country: United States

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