Disruption of the Aspergillus fumigatus gene encoding nucleolar protein CgrA impairs thermotolerant growth and reduces virulence.

Bhabhra, Ruchi; Miley, Michael D; Mylonakis, Eleftherios; Boettner, Doug; Fortwendel, Jarrod; Panepinto, John C; Postow, Michael; Rhodes, Judith C; Askew, David S

Bhabhra, Ruchi; Miley, Michael D; Mylonakis, Eleftherios; Boettner, Doug; Fortwendel, Jarrod; Panepinto, John C; Postow, Michael; Rhodes, Judith C; Askew, David S.

Affiliation

Bhabhra R; Department of Pathology and Laboratory Medicine, University of Cincinnati College of Medicine, 231 Bethesda Ave., OH 45267-0529, USA.

Infect Immun ; 72(8): 4731-40, 2004 Aug.

Article in En | MEDLINE | ID: mdl-15271935

Subject(s)

Aspergillus fumigatus/growth & development; Aspergillus fumigatus/pathogenicity; Fungal Proteins/genetics; Gene Deletion; Hot Temperature; Nuclear Proteins/genetics; Animals; Aspergillosis/microbiology; Aspergillosis/pathology; Aspergillus fumigatus/genetics; Disease Models, Animal; Drosophila/microbiology; Lung/pathology; Lung Diseases, Fungal/microbiology; Lung Diseases, Fungal/pathology; Mice; RNA-Binding Proteins; Virulence

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aspergillus fumigatus / Fungal Proteins / Nuclear Proteins / Gene Deletion / Hot Temperature Type of study: Prognostic_studies Limits: Animals Language: En Journal: Infect Immun Year: 2004 Document type: Article Affiliation country: United States Country of publication: United States

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