Probes for narcotic receptor-mediated phenomena. 33. Construction of a strained trans-5,6-ring system by displacement of a nitro-activated aromatic fluorine. synthesis of the penultimate oxide-bridged phenylmorphans.

Hashimoto, Akihiro; Przybyl, Anna K; Linders, Joannes T M; Kodato, Shinichi; Tian, Xinrong; Deschamps, Jeffrey R; George, Clifford; Flippen-Anderson, Judith L; Jacobson, Arthur E; Rice, Kenner C

Hashimoto, Akihiro; Przybyl, Anna K; Linders, Joannes T M; Kodato, Shinichi; Tian, Xinrong; Deschamps, Jeffrey R; George, Clifford; Flippen-Anderson, Judith L; Jacobson, Arthur E; Rice, Kenner C.

Affiliation

Hashimoto A; Laboratory of Medicinal Chemistry, National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, 20892-0815, USA.

J Org Chem ; 69(16): 5322-7, 2004 Aug 06.

Article in En | MEDLINE | ID: mdl-15287777

Subject(s)

Bridged-Ring Compounds; Molecular Probes/chemical synthesis; Morphinans/chemical synthesis; Receptors, Opioid/metabolism; Bridged-Ring Compounds/chemistry; Crystallography, X-Ray; Fluorine/chemistry; Molecular Structure; Stereoisomerism

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Collection: 01-internacional Database: MEDLINE Main subject: Bridged-Ring Compounds / Molecular Probes / Receptors, Opioid / Morphinans Language: En Journal: J Org Chem Year: 2004 Document type: Article Affiliation country: United States Country of publication: United States

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