Insulin-mediated activation of activator protein-1 through the mitogen-activated protein kinase pathway stimulates collagenase-1 gene transcription in the MES 13 mesangial cell line.

Ayala, J E; Boustead, J N; Chapman, S C; Svitek, C A; Oeser, J K; Robey, R B; O'Brien, R M

Ayala, J E; Boustead, J N; Chapman, S C; Svitek, C A; Oeser, J K; Robey, R B; O'Brien, R M.

Affiliation

Ayala JE; Department of Molecular Physiology and Biophysics, 761 PRB (MRB II), Vanderbilt University Medical School, Nashville, Tennessee 37232-0615, USA.

J Mol Endocrinol ; 33(1): 263-80, 2004 Aug.

Article in En | MEDLINE | ID: mdl-15291758

Subject(s)

Collagenases/genetics; Glomerular Mesangium/enzymology; Insulin/physiology; MAP Kinase Signaling System; Transcription Factor AP-1/physiology; Transcription, Genetic/physiology; Animals; Artificial Gene Fusion; Base Sequence; Cell Line; DNA Primers; Glomerular Mesangium/cytology; Humans; Mice; Plasmids; Promoter Regions, Genetic

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Collection: 01-internacional Database: MEDLINE Main subject: Transcription, Genetic / Collagenases / Transcription Factor AP-1 / MAP Kinase Signaling System / Glomerular Mesangium / Insulin Limits: Animals / Humans Language: En Journal: J Mol Endocrinol Journal subject: BIOLOGIA MOLECULAR / ENDOCRINOLOGIA Year: 2004 Document type: Article Affiliation country: United States Country of publication: United kingdom

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