TIN2 binds TRF1 and TRF2 simultaneously and stabilizes the TRF2 complex on telomeres.

Ye, Jeffrey Zheng-Sheng; Donigian, Jill R; van Overbeek, Megan; Loayza, Diego; Luo, Yan; Krutchinsky, Andrew N; Chait, Brian T; de Lange, Titia

Ye, Jeffrey Zheng-Sheng; Donigian, Jill R; van Overbeek, Megan; Loayza, Diego; Luo, Yan; Krutchinsky, Andrew N; Chait, Brian T; de Lange, Titia.

Affiliation

Ye JZ; Laboratory for Cell Biology and Genetics, the Rockefeller University, New York, New York 10021, USA.

J Biol Chem ; 279(45): 47264-71, 2004 Nov 05.

Article in En | MEDLINE | ID: mdl-15316005

Subject(s)

Cell Adhesion Molecules/chemistry; Membrane Glycoproteins/chemistry; Telomere/ultrastructure; Telomeric Repeat Binding Protein 1/metabolism; Telomeric Repeat Binding Protein 2/metabolism; Antigens, Surface; Blotting, Western; Cell Adhesion Molecules/metabolism; Cell Nucleus/metabolism; Chromatography, Gel; DNA Damage; Electrophoresis, Polyacrylamide Gel; Escherichia coli/metabolism; Gene Deletion; Glutathione Transferase/metabolism; Green Fluorescent Proteins/metabolism; HeLa Cells; Humans; Immunoprecipitation; Mass Spectrometry; Membrane Glycoproteins/metabolism; Phenotype; Protein Binding; Protein Structure, Tertiary; RNA Interference; RNA, Small Interfering/metabolism; Telomere/metabolism; Two-Hybrid System Techniques; beta-Galactosidase/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Membrane Glycoproteins / Cell Adhesion Molecules / Telomere / Telomeric Repeat Binding Protein 1 / Telomeric Repeat Binding Protein 2 Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Biol Chem Year: 2004 Document type: Article Affiliation country: United States Country of publication: United States

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