Extracellular nucleotide signaling by P2 receptors inhibits IL-12 and enhances IL-23 expression in human dendritic cells: a novel role for the cAMP pathway.

Schnurr, Max; Toy, Tracey; Shin, Amanda; Wagner, Moritz; Cebon, Jonathan; Maraskovsky, Eugene

Schnurr, Max; Toy, Tracey; Shin, Amanda; Wagner, Moritz; Cebon, Jonathan; Maraskovsky, Eugene.

Affiliation

Schnurr M; Ludwig Institute for Cancer Research, Austin Health, Heidelberg, Victoria 3084, Australia.

Blood ; 105(4): 1582-9, 2005 Feb 15.

Article in En | MEDLINE | ID: mdl-15486065

Subject(s)

Adenosine Triphosphate/physiology; Cyclic AMP/physiology; Dendritic Cells/metabolism; Extracellular Space/physiology; Interleukin-12/antagonists & inhibitors; Interleukins/biosynthesis; Receptors, Purinergic P2/physiology; Signal Transduction/immunology; Adenosine Triphosphate/pharmacology; Animals; Cells, Cultured; Dendritic Cells/immunology; Down-Regulation/immunology; Escherichia coli/immunology; Extracellular Space/metabolism; Humans; Immunologic Memory; Interferon-gamma/antagonists & inhibitors; Interferon-gamma/biosynthesis; Interleukin-12/biosynthesis; Interleukin-23; Interleukin-23 Subunit p19; Interleukins/metabolism; Mice; Monocytes/immunology; Monocytes/metabolism; Orthomyxoviridae/immunology; Resting Phase, Cell Cycle/immunology; T-Lymphocyte Subsets/cytology; T-Lymphocyte Subsets/immunology; T-Lymphocyte Subsets/metabolism; Up-Regulation/immunology

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Dendritic Cells / Signal Transduction / Adenosine Triphosphate / Interleukins / Receptors, Purinergic P2 / Cyclic AMP / Interleukin-12 / Extracellular Space Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Blood Year: 2005 Document type: Article Affiliation country: Australia Country of publication: United States

Search on Google

Add to My VHL

XML

PubMed Links