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Short interfering RNA (siRNA) targeting the Lyn kinase induces apoptosis in primary, and drug-resistant, BCR-ABL1(+) leukemia cells.
Ptasznik, Andrzej; Nakata, Yuji; Kalota, Anna; Emerson, Stephen G; Gewirtz, Alan M.
Affiliation
  • Ptasznik A; Division of Hematology/Oncology, Department of Medicine and Abramson Cancer Center, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA. andrzejp@mail.med.upenn.edu
Nat Med ; 10(11): 1187-9, 2004 Nov.
Article in En | MEDLINE | ID: mdl-15502840
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Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Blast Crisis / Fusion Proteins, bcr-abl / Apoptosis / Src-Family Kinases / RNA, Small Interfering Limits: Humans Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2004 Document type: Article Affiliation country: United States Country of publication: United States
Search on Google
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PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Blast Crisis / Fusion Proteins, bcr-abl / Apoptosis / Src-Family Kinases / RNA, Small Interfering Limits: Humans Language: En Journal: Nat Med Journal subject: BIOLOGIA MOLECULAR / MEDICINA Year: 2004 Document type: Article Affiliation country: United States Country of publication: United States