Perforin and Fas act together in the induction of apoptosis, and both are critical in the clearance of lymphocytic choriomeningitis virus infection.

Rode, Miriam; Balkow, Sandra; Sobek, Vera; Brehm, Reina; Martin, Praxedis; Kersten, Astrid; Dumrese, Tilman; Stehle, Thomas; Müllbacher, Arno; Wallich, Reinhard; Simon, Markus M

Rode, Miriam; Balkow, Sandra; Sobek, Vera; Brehm, Reina; Martin, Praxedis; Kersten, Astrid; Dumrese, Tilman; Stehle, Thomas; Müllbacher, Arno; Wallich, Reinhard; Simon, Markus M.

Affiliation

Rode M; Max-Planck-Institut für Immunbiologie, Stübeweg 51, D-79108 Freiburg, Germany.

J Virol ; 78(22): 12395-405, 2004 Nov.

Article in En | MEDLINE | ID: mdl-15507626

Subject(s)

Apoptosis; Lymphocytic Choriomeningitis/immunology; Membrane Glycoproteins/physiology; fas Receptor/physiology; Animals; Antigens, Differentiation/physiology; Endopeptidases/physiology; Fas Ligand Protein; Granzymes; Lymphocytic Choriomeningitis/metabolism; Lymphocytic Choriomeningitis/pathology; Mice; Mice, Inbred BALB C; Perforin; Pore Forming Cytotoxic Proteins; Reactive Oxygen Species/metabolism; Serine Endopeptidases/physiology; T-Lymphocytes, Cytotoxic/immunology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Membrane Glycoproteins / Apoptosis / Fas Receptor / Lymphocytic Choriomeningitis Limits: Animals Language: En Journal: J Virol Year: 2004 Document type: Article Affiliation country: Germany Country of publication: United States

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