Self-complementary adeno-associated virus 2 (AAV)-T cell protein tyrosine phosphatase vectors as helper viruses to improve transduction efficiency of conventional single-stranded AAV vectors in vitro and in vivo.

Zhong, Li; Chen, Linyuan; Li, Yanjun; Qing, Keyun; Weigel-Kelley, Kirsten A; Chan, Rebecca J; Yoder, Mervin C; Srivastava, Arun

Zhong, Li; Chen, Linyuan; Li, Yanjun; Qing, Keyun; Weigel-Kelley, Kirsten A; Chan, Rebecca J; Yoder, Mervin C; Srivastava, Arun.

Affiliation

Zhong L; Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis 46202, USA.

Mol Ther ; 10(5): 950-7, 2004 Nov.

Article in En | MEDLINE | ID: mdl-15509512

Subject(s)

Dependovirus/genetics; Genetic Vectors/genetics; Helper Viruses/genetics; Protein Tyrosine Phosphatases/genetics; Transduction, Genetic/methods; Animals; Cell Line, Tumor; DNA, Viral/analysis; Genetic Therapy/methods; Green Fluorescent Proteins/analysis; Green Fluorescent Proteins/genetics; Hepatocytes/chemistry; Hepatocytes/pathology; Humans; Mice; Mice, Inbred C57BL; Protein Tyrosine Phosphatase, Non-Receptor Type 2; Protein Tyrosine Phosphatases/analysis; Protein Tyrosine Phosphatases/metabolism

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Transduction, Genetic / Protein Tyrosine Phosphatases / Dependovirus / Genetic Vectors / Helper Viruses Type of study: Risk_factors_studies Limits: Animals / Humans Language: En Journal: Mol Ther Journal subject: BIOLOGIA MOLECULAR / TERAPEUTICA Year: 2004 Document type: Article Affiliation country: United States Country of publication: United States

Search on Google

Add to My VHL

XML

PubMed Links