Retinoid X receptor regulates Nur77/TR3-dependent apoptosis [corrected] by modulating its nuclear export and mitochondrial targeting.

Cao, Xihua; Liu, Wen; Lin, Feng; Li, Hui; Kolluri, Siva Kumar; Lin, Bingzhen; Han, Young-hoon; Dawson, Marcia I; Zhang, Xiao-kun

Cao, Xihua; Liu, Wen; Lin, Feng; Li, Hui; Kolluri, Siva Kumar; Lin, Bingzhen; Han, Young-hoon; Dawson, Marcia I; Zhang, Xiao-kun.

Affiliation

Cao X; The Burnham Institute, Cancer Center, 10901 N. Torrey Pines Rd., La Jolla, CA 92037, USA.

Mol Cell Biol ; 24(22): 9705-25, 2004 Nov.

Article in En | MEDLINE | ID: mdl-15509776

Subject(s)

Apoptosis/physiology; DNA-Binding Proteins/metabolism; Retinoid X Receptor alpha/metabolism; Transcription Factors/metabolism; Active Transport, Cell Nucleus; Amino Acid Sequence; Animals; Apoptosis/drug effects; Base Sequence; Cell Line; DNA/genetics; DNA-Binding Proteins/chemistry; DNA-Binding Proteins/genetics; Dimerization; Humans; Mitochondria/metabolism; Molecular Sequence Data; Mutation; Nuclear Receptor Subfamily 4, Group A, Member 1; Proto-Oncogene Proteins c-bcl-2/metabolism; RNA, Small Interfering/genetics; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Receptors, Thyroid Hormone/chemistry; Receptors, Thyroid Hormone/genetics; Receptors, Thyroid Hormone/metabolism; Recombinant Fusion Proteins/genetics; Recombinant Fusion Proteins/metabolism; Retinoid X Receptor alpha/chemistry; Retinoid X Receptor alpha/genetics; Tetradecanoylphorbol Acetate/pharmacology; Transcription Factors/chemistry; Transcription Factors/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / Apoptosis / Retinoid X Receptor alpha / DNA-Binding Proteins Limits: Animals / Humans Language: En Journal: Mol Cell Biol Year: 2004 Document type: Article Affiliation country: United States

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