[A multiple myeloma long term survival case]. / Survie prolongee au cours du myelome multiple: à propos d'une observation.
Tunis Med
; 82(6): 538-41, 2004 Jun.
Article
in Fr
| MEDLINE
| ID: mdl-15517953
ABSTRACT
Multiple myeloma is a malignant plasma cells proliferation in the bone marrow leading to a monoclonal immunoglobulin hypersecretion. The survival duration of this disease ranges usually from 2 to 3 years. However, as this reported case, a long-term survival remains possible. A 29 year old woman was admitted to the internal medicine department for bone pain, weight loss and pathologic fractures. The clinical examination revealed an anaemia, a spinal compression (D10) and atrophia of quadriceps and gluteus muscle. The radiologic findings observed were multiple fractures. The bone marrow aspiration confirmed the plasmocytosis greater than 50%, with immature plasma cells and other lineages rarefication. The disease belonged to the stage III A of the Salmon and Durie classification. Chemotherapy with melphalan associated to prednisone was started with a two to three months biological and clinical follow-up. This treatment allowed 12 years survival. Because of this variety, the search for new prognostic factors would be relevant.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Multiple Myeloma
Type of study:
Prognostic_studies
Limits:
Adult
/
Female
/
Humans
Language:
Fr
Journal:
Tunis Med
Year:
2004
Document type:
Article