A novel class of calcium-entry blockers: the 1[[4-(aminoalkoxy)phenyl]sulfonyl]indolizines.

Gubin, J; Lucchetti, J; Mahaux, J; Nisato, D; Rosseels, G; Clinet, M; Polster, P; Chatelain, P

Gubin, J; Lucchetti, J; Mahaux, J; Nisato, D; Rosseels, G; Clinet, M; Polster, P; Chatelain, P.

Affiliation

Gubin J; Sanofi Research Center, Brussels, Belgium.

J Med Chem ; 35(6): 981-8, 1992 Mar 20.

Article in En | MEDLINE | ID: mdl-1552511

Subject(s)

Calcium Channel Blockers/chemical synthesis; Indolizines/chemical synthesis; Phenethylamines/chemical synthesis; Animals; Binding Sites/drug effects; Brain/drug effects; Brain/metabolism; Calcium Channel Blockers/chemistry; Calcium Channel Blockers/pharmacology; Guinea Pigs; Indolizines/chemistry; Indolizines/pharmacology; Male; Phenethylamines/pharmacology; Rats; Rats, Inbred Strains; Structure-Activity Relationship

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Collection: 01-internacional Database: MEDLINE Main subject: Phenethylamines / Calcium Channel Blockers / Indolizines Limits: Animals Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 1992 Document type: Article Affiliation country: Belgium Country of publication: United States

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