Caspase-mediated apoptosis and caspase-independent cell death induced by irofulven in prostate cancer cells.

Liang, Huiyun; Salinas, Richard A; Leal, Belinda Z; Kosakowska-Cholody, Teresa; Michejda, Christopher J; Waters, Stephen J; Herman, Terence S; Woynarowski, Jan M; Woynarowska, Barbara A

Liang, Huiyun; Salinas, Richard A; Leal, Belinda Z; Kosakowska-Cholody, Teresa; Michejda, Christopher J; Waters, Stephen J; Herman, Terence S; Woynarowski, Jan M; Woynarowska, Barbara A.

Affiliation

Liang H; Department of Radiation Oncology, University of Texas Health Science Center, IDD Building, 14960 Omicron Drive, San Antonio, TX 78245, USA.

Mol Cancer Ther ; 3(11): 1385-96, 2004 Nov.

Article in En | MEDLINE | ID: mdl-15542777

Subject(s)

Apoptosis/drug effects; Caspases/metabolism; Enzyme Inhibitors/pharmacology; Prostatic Neoplasms/enzymology; Prostatic Neoplasms/pathology; Sesquiterpenes/pharmacology; Bridged Bicyclo Compounds/pharmacology; Cell Line, Tumor; Cell Proliferation/drug effects; Cytochromes c/metabolism; DNA Fragmentation/drug effects; Enzyme Inhibitors/chemistry; Humans; Male; Mitochondria/drug effects; Mitochondria/metabolism; Molecular Structure; Prostatic Neoplasms/metabolism; Protein Transport/drug effects; Proto-Oncogene Proteins c-bcl-2/metabolism; Sesquiterpenes/chemistry; Signal Transduction/drug effects; bcl-2-Associated X Protein

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Collection: 01-internacional Database: MEDLINE Main subject: Prostatic Neoplasms / Sesquiterpenes / Apoptosis / Caspases / Enzyme Inhibitors Limits: Humans / Male Language: En Journal: Mol Cancer Ther Journal subject: ANTINEOPLASICOS Year: 2004 Document type: Article Affiliation country: United States Country of publication: United States

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