Epitope-specific crosslinking of CD45 down-regulates membrane-associated tyrosine phosphatase activity and triggers early signalling events in human activated T cells.

Spertini, François; Perret-Menoud, Veronique; Barbier, Nathalie; Chatila, Talal; Barbey, Catherine; Corthesy, Blaise

Spertini, François; Perret-Menoud, Veronique; Barbier, Nathalie; Chatila, Talal; Barbey, Catherine; Corthesy, Blaise.

Affiliation

Spertini F; Division of Immunology and Allergy, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland. francois.spertini@chuv.hospvd.ch

Immunology ; 113(4): 441-52, 2004 Dec.

Article in En | MEDLINE | ID: mdl-15554922

Subject(s)

Down-Regulation/immunology; Leukocyte Common Antigens/immunology; Protein Tyrosine Phosphatases/metabolism; Signal Transduction/immunology; T-Lymphocytes/immunology; Cells, Cultured; Epitopes, T-Lymphocyte/immunology; Humans; Lymphocyte Activation/immunology; Phosphorylation; Tumor Necrosis Factor-alpha/biosynthesis; Tumor Necrosis Factor-alpha/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes / Signal Transduction / Down-Regulation / Protein Tyrosine Phosphatases / Leukocyte Common Antigens Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Immunology Year: 2004 Document type: Article Affiliation country: Switzerland Country of publication: United kingdom

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