Two Kir2.1 channel populations with different sensitivities to Mg(2+) and polyamine block: a model for the cardiac strong inward rectifier K(+) channel.

Yan, Ding-Hong; Ishihara, Keiko

Yan, Ding-Hong; Ishihara, Keiko.

Affiliation

Yan DH; Department of Physiology, Faculty of Medicine, Saga University, 5-1-1 Nabeshima, Saga 849-8501, Japan.

J Physiol ; 563(Pt 3): 725-44, 2005 Mar 15.

Article in En | MEDLINE | ID: mdl-15618275

Subject(s)

Ion Channel Gating/physiology; Magnesium/pharmacology; Membrane Potentials/physiology; Myocytes, Cardiac/physiology; Polyamines/metabolism; Potassium Channels, Inwardly Rectifying/physiology; Spermine/pharmacology; Animals; Cell Line; Dose-Response Relationship, Drug; Humans; Ion Channel Gating/drug effects; Kidney/drug effects; Kidney/physiology; Membrane Potentials/drug effects; Mice; Models, Biological; Myocytes, Cardiac/drug effects; Polyamines/antagonists & inhibitors; Potassium Channels, Inwardly Rectifying/classification; Potassium Channels, Inwardly Rectifying/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polyamines / Spermine / Ion Channel Gating / Potassium Channels, Inwardly Rectifying / Myocytes, Cardiac / Magnesium / Membrane Potentials Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: J Physiol Year: 2005 Document type: Article Affiliation country: Japan Country of publication: United kingdom

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