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Inhibition of human CYP2B6 by N,N',N''-triethylenethiophosphoramide is irreversible and mechanism-based.
Richter, Tanja; Schwab, Matthias; Eichelbaum, Michel; Zanger, Ulrich M.
Affiliation
  • Richter T; Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology, Auerbachstr. 112, 70376 Stuttgart, Germany.
Biochem Pharmacol ; 69(3): 517-24, 2005 Feb 01.
Article in En | MEDLINE | ID: mdl-15652242
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Collection: 01-internacional Database: MEDLINE Main subject: Oxidoreductases, N-Demethylating / Aryl Hydrocarbon Hydroxylases / Thiotepa / Enzyme Inhibitors Limits: Humans Language: En Journal: Biochem Pharmacol Year: 2005 Document type: Article Affiliation country: Germany Country of publication: United kingdom
Search on Google
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PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Oxidoreductases, N-Demethylating / Aryl Hydrocarbon Hydroxylases / Thiotepa / Enzyme Inhibitors Limits: Humans Language: En Journal: Biochem Pharmacol Year: 2005 Document type: Article Affiliation country: Germany Country of publication: United kingdom