Relation of QTc duration heterogeneity to mortality following orthotopic heart transplantation.
Am J Cardiol
; 95(3): 431-2, 2005 Feb 01.
Article
in En
| MEDLINE
| ID: mdl-15670564
ABSTRACT
Studies of heart failure patients have demonstrated that serial QT prolongation and abnormally prolonged QT intervals are associated with greater mortality. Serial QT interval measurements in patients who undergo orthotopic heart transplantation (OHT) may quantify the degree of myocardial repolarization heterogeneity and serve as a marker of arrhythmogenic substrate. In this study, the mean survival for those with "stable" QT(c) intervals (a change of -10 to 10 ms/year) was 124 +/- 8 months versus 63 +/- 25 months in those with annual QT(c) changes of >10 ms (p = 0.009). Ventricular repolarization heterogeneity may serve as a marker of identifying high-risk patients after OHT.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Long QT Syndrome
/
Heart Transplantation
Type of study:
Prognostic_studies
Limits:
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Am J Cardiol
Year:
2005
Document type:
Article
Affiliation country:
United States