Protective effect of dexamethasone on osmotic-induced demyelination in rats.

Sugimura, Yoshihisa; Murase, Takashi; Takefuji, Seiko; Hayasaka, Shizu; Takagishi, Yoshiko; Oiso, Yutaka; Murata, Yoshiharu

Sugimura, Yoshihisa; Murase, Takashi; Takefuji, Seiko; Hayasaka, Shizu; Takagishi, Yoshiko; Oiso, Yutaka; Murata, Yoshiharu.

Affiliation

Sugimura Y; Department of Teratology and Genetics, Research Institute of Environmental Medicine, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan.

Exp Neurol ; 192(1): 178-83, 2005 Mar.

Article in En | MEDLINE | ID: mdl-15698632

Subject(s)

Blood-Brain Barrier/drug effects; Dexamethasone/pharmacology; Hypernatremia/complications; Hyponatremia/drug therapy; Myelinolysis, Central Pontine/prevention & control; Saline Solution, Hypertonic/adverse effects; Animals; Blood-Brain Barrier/physiopathology; Brain/drug effects; Brain/pathology; Brain/physiopathology; Deamino Arginine Vasopressin/pharmacology; Dexamethasone/therapeutic use; Disease Models, Animal; Hypernatremia/chemically induced; Hypernatremia/physiopathology; Hyponatremia/complications; Hyponatremia/physiopathology; Immunoglobulin G/metabolism; Male; Myelinolysis, Central Pontine/chemically induced; Myelinolysis, Central Pontine/physiopathology; Nerve Fibers, Myelinated/drug effects; Nerve Fibers, Myelinated/metabolism; Rats; Rats, Sprague-Dawley; Water-Electrolyte Balance/drug effects; Water-Electrolyte Balance/physiology

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Collection: 01-internacional Database: MEDLINE Main subject: Saline Solution, Hypertonic / Dexamethasone / Blood-Brain Barrier / Myelinolysis, Central Pontine / Hypernatremia / Hyponatremia Limits: Animals Language: En Journal: Exp Neurol Year: 2005 Document type: Article Affiliation country: Japan Country of publication: United States

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