Structural and mechanistic studies of chloride induced activation of human pancreatic alpha-amylase.

Maurus, Robert; Begum, Anjuman; Kuo, Hsin-Hen; Racaza, Andrew; Numao, Shin; Andersen, Carsten; Tams, Jeppe W; Vind, Jesper; Overall, Christopher M; Withers, Stephen G; Brayer, Gary D

Maurus, Robert; Begum, Anjuman; Kuo, Hsin-Hen; Racaza, Andrew; Numao, Shin; Andersen, Carsten; Tams, Jeppe W; Vind, Jesper; Overall, Christopher M; Withers, Stephen G; Brayer, Gary D.

Affiliation

Maurus R; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada V6T 1Z3.

Protein Sci ; 14(3): 743-55, 2005 Mar.

Article in En | MEDLINE | ID: mdl-15722449

Subject(s)

Chlorides/metabolism; Pancreas/enzymology; alpha-Amylases/chemistry; Acarbose/metabolism; Amino Acid Sequence; Amino Acid Substitution; Aspergillus oryzae/enzymology; Aspergillus oryzae/genetics; Enzyme Activation/physiology; Humans; Hydrogen Bonding; Kinetics; Mutagenesis; Pancreas/metabolism; Protein Structure, Tertiary; Sequence Alignment; alpha-Amylases/genetics; alpha-Amylases/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreas / Chlorides / Alpha-Amylases Limits: Humans Language: En Journal: Protein Sci Journal subject: BIOQUIMICA Year: 2005 Document type: Article Country of publication: United States

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