Developments in the rat adjuvant arthritis model and its use in therapeutic evaluation of novel non-invasive treatment by SOD in Transfersomes.

Simões, S I; Delgado, T C; Lopes, R M; Jesus, S; Ferreira, A A; Morais, J A; Cruz, M E M; Corvo, M L; Martins, M B F

Simões, S I; Delgado, T C; Lopes, R M; Jesus, S; Ferreira, A A; Morais, J A; Cruz, M E M; Corvo, M L; Martins, M B F.

Affiliation

Simões SI; Unidade de Novas Formas de Agentes Bioactivos, Departamento de Biotecnologia, Instituto Nacional de Engenharia, Tecnologia e Inovação, Edifício F, Estrada do Paço do Lumiar, 22 1649-038 Lisboa, Portugal. sandra.simoes@ineti.pt

J Control Release ; 103(2): 419-34, 2005 Mar 21.

Article in En | MEDLINE | ID: mdl-15763624

Subject(s)

Anti-Inflammatory Agents, Non-Steroidal/therapeutic use; Arthritis, Experimental/drug therapy; Drug Carriers/administration & dosage; Superoxide Dismutase/therapeutic use; Animals; Anti-Inflammatory Agents, Non-Steroidal/administration & dosage; Anti-Inflammatory Agents, Non-Steroidal/chemistry; Arthritis, Experimental/blood; Arthritis, Experimental/diagnostic imaging; Ascorbic Acid/blood; Drug Carriers/chemistry; Extremities/diagnostic imaging; Leukocyte Count; Liposomes; Male; Particle Size; Radiography; Rats; Rats, Wistar; Sulfhydryl Compounds/blood; Superoxide Dismutase/administration & dosage; Superoxide Dismutase/chemistry; Treatment Outcome

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Collection: 01-internacional Database: MEDLINE Main subject: Arthritis, Experimental / Superoxide Dismutase / Drug Carriers / Anti-Inflammatory Agents, Non-Steroidal Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals Language: En Journal: J Control Release Journal subject: FARMACOLOGIA Year: 2005 Document type: Article Affiliation country: Portugal

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