Comparison of the systemic pharmacodynamic effects and pharmacokinetics of salmeterol delivered by CFC propellant and non-CFC propellant metered dose inhalers in healthy subjects.

Kempsford, Rodger; Handel, Malcolm; Mehta, Rashmi; De Silva, Mariza; Daley-Yates, Peter

Kempsford, Rodger; Handel, Malcolm; Mehta, Rashmi; De Silva, Mariza; Daley-Yates, Peter.

Affiliation

Kempsford R; Clinical Pharmacology and Discovery Medicine, GlaxoSmithKline Research and Development, Greenford Road, Greenford, Middlesex UB6 0HE, UK. rodger.d.kempsford@gsk.com

Respir Med ; 99 Suppl A: S11-9, 2005 Apr.

Article in En | MEDLINE | ID: mdl-15777604

Subject(s)

Aerosol Propellants; Albuterol/analogs & derivatives; Albuterol/pharmacology; Anti-Asthmatic Agents/pharmacology; Asthma/physiopathology; Adolescent; Adult; Albuterol/administration & dosage; Albuterol/blood; Anti-Asthmatic Agents/administration & dosage; Anti-Asthmatic Agents/blood; Asthma/blood; Asthma/drug therapy; Chemical Phenomena; Chemistry, Physical; Chlorofluorocarbons; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Heart Rate/drug effects; Humans; Hydrocarbons, Fluorinated; Male; Metered Dose Inhalers; Middle Aged; Potassium/blood; Salmeterol Xinafoate

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Collection: 01-internacional Database: MEDLINE Main subject: Asthma / Anti-Asthmatic Agents / Aerosol Propellants / Albuterol Type of study: Clinical_trials Limits: Adolescent / Adult / Humans / Male / Middle aged Language: En Journal: Respir Med Year: 2005 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom

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