Application of division arrest technology to cell-based HTS: comparison with frozen and fresh cells.

Kunapuli, Priya; Zheng, Wei; Weber, Michael; Solly, Kelli; Mull, Rebecca; Platchek, Michael; Cong, Mei; Zhong, Zhong; Strulovici, Berta

Kunapuli, Priya; Zheng, Wei; Weber, Michael; Solly, Kelli; Mull, Rebecca; Platchek, Michael; Cong, Mei; Zhong, Zhong; Strulovici, Berta.

Affiliation

Kunapuli P; Department of Automated Biotechnology, Merck Research Laboratories, North Wales, PA 19454, USA. priya_kunapuli@merck.com

Assay Drug Dev Technol ; 3(1): 17-26, 2005 Feb.

Article in En | MEDLINE | ID: mdl-15798392

Subject(s)

Biological Assay/methods; Calcium/pharmacology; Cell Culture Techniques/methods; Cell Cycle/physiology; Cryopreservation/methods; GTP-Binding Protein alpha Subunits, Gq-G11/metabolism; Mitomycin/pharmacology; Animals; CHO Cells; Cell Cycle/drug effects; Cell Line; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Drug Design; GTP-Binding Protein alpha Subunits, Gq-G11/genetics; Reproducibility of Results; Robotics/methods; Sensitivity and Specificity; Spectrometry, Fluorescence/methods

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Collection: 01-internacional Database: MEDLINE Main subject: Biological Assay / Cryopreservation / Cell Cycle / Calcium / Mitomycin / Cell Culture Techniques / GTP-Binding Protein alpha Subunits, Gq-G11 Type of study: Diagnostic_studies / Evaluation_studies / Prognostic_studies Limits: Animals Language: En Journal: Assay Drug Dev Technol Journal subject: FARMACOLOGIA Year: 2005 Document type: Article Affiliation country: United States Country of publication: United States

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