Biological activity of for-Met-Leu-Phe-OMe analogs: relevant substitutions specifically trigger killing mechanisms in human neutrophils.

Cavicchioni, Giorgio; Fraulini, Anna; Turchetti, Marianna; Varani, Katia; Falzarano, Sofia; Pavan, Barbara; Spisani, Susanna

Cavicchioni, Giorgio; Fraulini, Anna; Turchetti, Marianna; Varani, Katia; Falzarano, Sofia; Pavan, Barbara; Spisani, Susanna.

Affiliation

Cavicchioni G; Department of Pharmaceutical Sciences, University of Ferrara, Via Fossato di Mortara 17/19, 44100 Ferrara, Italy. g5z@unife.it

Eur J Pharmacol ; 512(1): 1-8, 2005 Apr 04.

Article in En | MEDLINE | ID: mdl-15814083

Subject(s)

Cytotoxicity, Immunologic/drug effects; N-Formylmethionine Leucyl-Phenylalanine/analogs & derivatives; N-Formylmethionine Leucyl-Phenylalanine/pharmacology; Neutrophils/drug effects; Binding, Competitive; Chemotaxis, Leukocyte/drug effects; Humans; In Vitro Techniques; Muramidase/metabolism; N-Formylmethionine Leucyl-Phenylalanine/chemistry; Neutrophils/metabolism; Radioligand Assay; Structure-Activity Relationship; Superoxides/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Cytotoxicity, Immunologic / N-Formylmethionine Leucyl-Phenylalanine / Neutrophils Limits: Humans Language: En Journal: Eur J Pharmacol Year: 2005 Document type: Article Affiliation country: Italy Country of publication: Netherlands

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