Smooth muscle cells deficient in osteopontin have enhanced susceptibility to calcification in vitro.

Speer, Mei Y; Chien, Yung-Ching; Quan, Mary; Yang, Hsueh-Ying; Vali, Hojatollah; McKee, Marc D; Giachelli, Cecilia M

Speer, Mei Y; Chien, Yung-Ching; Quan, Mary; Yang, Hsueh-Ying; Vali, Hojatollah; McKee, Marc D; Giachelli, Cecilia M.

Affiliation

Speer MY; Bioengineering Department, Box 351720 University of Washington, Seattle, WA 98195, USA.

Cardiovasc Res ; 66(2): 324-33, 2005 May 01.

Article in En | MEDLINE | ID: mdl-15820201

Subject(s)

Calcinosis/etiology; Muscle, Smooth, Vascular/metabolism; Sialoglycoproteins/deficiency; Animals; Aorta; Calcinosis/metabolism; Cell Culture Techniques; DNA, Complementary/administration & dosage; Disease Susceptibility; Genetic Vectors/administration & dosage; Mice; Mice, Knockout; Osteopontin; Phosphates/pharmacology; Retroviridae/genetics; Sialoglycoproteins/genetics; Transduction, Genetic/methods

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Collection: 01-internacional Database: MEDLINE Main subject: Sialoglycoproteins / Calcinosis / Muscle, Smooth, Vascular Limits: Animals Language: En Journal: Cardiovasc Res Year: 2005 Document type: Article Affiliation country: United States Country of publication: United kingdom

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