N-linked keratan sulfate in the aggrecan interglobular domain potentiates aggrecanase activity.

Poon, Christopher J; Plaas, Anna H; Keene, Doug R; McQuillan, David J; Last, Karena; Fosang, Amanda J

Poon, Christopher J; Plaas, Anna H; Keene, Doug R; McQuillan, David J; Last, Karena; Fosang, Amanda J.

Affiliation

Poon CJ; Department of Paediatrics, University of Melbourne and Murdoch Childrens Research Institute, Arthritis Research Group, Royal Children's Hospital, Parkville, Victoria 3052, Australia.

J Biol Chem ; 280(25): 23615-21, 2005 Jun 24.

Article in En | MEDLINE | ID: mdl-15849197

Subject(s)

Endopeptidases/metabolism; Extracellular Matrix Proteins/metabolism; Keratan Sulfate/metabolism; Proteoglycans/metabolism; Aggrecans; Amino Acid Sequence; Base Sequence; DNA Primers; Extracellular Matrix Proteins/chemistry; Humans; Lectins, C-Type; Molecular Sequence Data; Protein Conformation; Proteoglycans/chemistry; Recombinant Proteins/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Endopeptidases / Proteoglycans / Extracellular Matrix Proteins / Keratan Sulfate Limits: Humans Language: En Journal: J Biol Chem Year: 2005 Document type: Article Affiliation country: Australia Country of publication: United States

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