The role of the N-methyl-D-aspartate receptor in ketamine-induced apoptosis in rat forebrain culture.

Wang, C; Sadovova, N; Fu, X; Schmued, L; Scallet, A; Hanig, J; Slikker, W

Wang, C; Sadovova, N; Fu, X; Schmued, L; Scallet, A; Hanig, J; Slikker, W.

Affiliation

Wang C; Division of Neurotoxicology, National Center for Toxicological Research, Food and Drug Administration, Jefferson, AR 72079-0502, USA. cwang@nctr.fda.gov

Neuroscience ; 132(4): 967-77, 2005.

Article in En | MEDLINE | ID: mdl-15857702

Subject(s)

Anesthetics, Dissociative/toxicity; Apoptosis/drug effects; Ketamine/toxicity; Prosencephalon/drug effects; Prosencephalon/pathology; Receptors, N-Methyl-D-Aspartate/metabolism; Animals; Blotting, Western; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; In Situ Nick-End Labeling; Oligonucleotides, Antisense/pharmacology; Prosencephalon/metabolism; Proto-Oncogene Proteins c-bcl-2/drug effects; Proto-Oncogene Proteins c-bcl-2/metabolism; Rats; Thionucleotides/pharmacology; bcl-2-Associated X Protein

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Collection: 01-internacional Database: MEDLINE Main subject: Prosencephalon / Apoptosis / Receptors, N-Methyl-D-Aspartate / Ketamine / Anesthetics, Dissociative Limits: Animals Language: En Journal: Neuroscience Year: 2005 Document type: Article Affiliation country: United States Country of publication: United States

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