Hypoxia-regulated glucose transporter Glut-1 may influence chemosensitivity to some alkylating agents: results of EORTC (First Translational Award) study of the relevance of tumour hypoxia to the outcome of chemotherapy in human tumour-derived xenografts.

Airley, R E; Phillips, R M; Evans, A E; Double, J; Burger, A M; Feibig, H H; West, C M L; Stratford, I J

Airley, R E; Phillips, R M; Evans, A E; Double, J; Burger, A M; Feibig, H H; West, C M L; Stratford, I J.

Affiliation

Airley RE; School of Pharmacy and Chemistry, Liverpool John Moores University, Liverpool, L3 3AF, UK. r.airley@livjm.ac.uk

Int J Oncol ; 26(6): 1477-84, 2005 Jun.

Article in En | MEDLINE | ID: mdl-15870859

Subject(s)

Antineoplastic Agents, Alkylating/pharmacology; Monosaccharide Transport Proteins/physiology; Neoplasms, Experimental/drug therapy; Animals; Biomarkers; Cell Hypoxia; Endoplasmic Reticulum Chaperone BiP; Glucose Transporter Type 1; Heat-Shock Proteins/physiology; Humans; Mice; Molecular Chaperones/physiology; Neoplasm Transplantation; Neoplasms, Experimental/metabolism; Transplantation, Heterologous

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Collection: 01-internacional Database: MEDLINE Main subject: Monosaccharide Transport Proteins / Antineoplastic Agents, Alkylating / Neoplasms, Experimental Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Int J Oncol Journal subject: NEOPLASIAS Year: 2005 Document type: Article Affiliation country: United kingdom Country of publication: Greece

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