Multifocal bone marrow involvement in cat-scratch disease.

Hipp, Sean J; O'Shields, Ashley; Fordham, Lynn A; Blatt, Julie; Hamrick, Harvey J; Henderson, Frederick W

Hipp, Sean J; O'Shields, Ashley; Fordham, Lynn A; Blatt, Julie; Hamrick, Harvey J; Henderson, Frederick W.

Affiliation

Hipp SJ; Departments of Pediatrics, University of North Carolina, Chapel Hill, NC 27599-7593, USA. shipp@unch.unc.edu

Pediatr Infect Dis J ; 24(5): 472-4, 2005 May.

Article in En | MEDLINE | ID: mdl-15876956

ABSTRACT

ABSTRACT

We describe 2 children with prolonged fever of unknown origin and prominent skeletal pain who had multifocal bone disease caused by Bartonella infection. Initial radiologic studies, including plain films, radionuclide scintigraphy and computed tomography, yielded negative results. In both cases, magnetic resonance imaging revealed multiple enhancing bone marrow lesions consistent with clinical symptoms. Microbiologic diagnoses were established serologically.

Subject(s)

Bartonella henselae/isolation & purification; Bone Marrow/pathology; Cat-Scratch Disease/diagnosis; Osteomyelitis/diagnosis; Osteomyelitis/microbiology; Animals; Anti-Bacterial Agents/therapeutic use; Bone Marrow/microbiology; Cat-Scratch Disease/complications; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Magnetic Resonance Imaging/methods; Male; Osteomyelitis/drug therapy; Risk Assessment; Severity of Illness Index; Tomography, X-Ray Computed/methods; Treatment Outcome

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Osteomyelitis / Bone Marrow / Cat-Scratch Disease / Bartonella henselae Type of study: Etiology_studies / Observational_studies / Prognostic_studies Limits: Animals / Child / Child, preschool / Female / Humans / Male Language: En Journal: Pediatr Infect Dis J Journal subject: DOENCAS TRANSMISSIVEIS / PEDIATRIA Year: 2005 Document type: Article Affiliation country: United States

Search on Google

Add to My VHL

XML

PubMed Links