High performance liquid chromatographic methods for the determination of aripiprazole with ultraviolet detection in rat plasma and brain: application to the pharmacokinetic study.

Shimokawa, Yoshihiko; Akiyama, Hitoshi; Kashiyama, Eiji; Koga, Toshihisa; Miyamoto, Gohachiro

Shimokawa, Yoshihiko; Akiyama, Hitoshi; Kashiyama, Eiji; Koga, Toshihisa; Miyamoto, Gohachiro.

Affiliation

Shimokawa Y; Tokushima Research Institute, Otsuka Pharmaceutical Co. Ltd., 463-10 Kagasuno, Kawauchi-cho, Tokushima 771-0192, Japan. y_shimokawa@research.otsuka.co.jp

J Chromatogr B Analyt Technol Biomed Life Sci ; 821(1): 8-14, 2005 Jul 05.

Article in En | MEDLINE | ID: mdl-15897016

Subject(s)

Antipsychotic Agents/analysis; Chromatography, High Pressure Liquid/methods; Piperazines/analysis; Quinolones/analysis; Animals; Antipsychotic Agents/blood; Antipsychotic Agents/pharmacokinetics; Aripiprazole; Brain Chemistry; Drug Stability; Freezing; Male; Piperazines/blood; Piperazines/pharmacokinetics; Quinolones/blood; Quinolones/pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet

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Collection: 01-internacional Database: MEDLINE Main subject: Piperazines / Antipsychotic Agents / Chromatography, High Pressure Liquid / Quinolones Type of study: Diagnostic_studies Limits: Animals Language: En Journal: J Chromatogr B Analyt Technol Biomed Life Sci Journal subject: ENGENHARIA BIOMEDICA Year: 2005 Document type: Article Affiliation country: Japan Country of publication: Netherlands

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