Imino sugar inhibitors for treating the lysosomal glycosphingolipidoses.

Butters, Terry D; Dwek, Raymond A; Platt, Frances M

Butters, Terry D; Dwek, Raymond A; Platt, Frances M.

Affiliation

Butters TD; Department of Biochemistry, Oxford Glycobiology Institute, University of Oxford, South Parks Road, Oxford OX1 3QU, UK. terry.butters@bioch.ox.ac.uk

Glycobiology ; 15(10): 43R-52R, 2005 Oct.

Article in En | MEDLINE | ID: mdl-15901676

Subject(s)

Enzyme Inhibitors/therapeutic use; Glycosphingolipids/metabolism; Imino Sugars/therapeutic use; Sphingolipidoses/drug therapy; Animals; Drug Evaluation, Preclinical; Gaucher Disease/drug therapy; Glucosyltransferases/antagonists & inhibitors; Glycosphingolipids/antagonists & inhibitors; Glycosphingolipids/biosynthesis; Humans; Sphingolipidoses/enzymology

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Collection: 01-internacional Database: MEDLINE Main subject: Glycosphingolipids / Sphingolipidoses / Enzyme Inhibitors / Imino Sugars Limits: Animals / Humans Language: En Journal: Glycobiology Journal subject: BIOQUIMICA Year: 2005 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom

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